Does low testosterone in men lead to difficulties with concentration and memory ?

Does low testosterone in men lead to difficulties with concentration and memory ?

The role of sex hormones in the prevention of cognitive decline is uncertain.

Some people say they have trouble remembering shopping lists, doing mental arithmetic, or finding the right word in conversation. Problems with memory and thought processes can be difficult to assess. The changes are subtle and are particularly difficult to pick up.  Doctors call this mild cognitive impairment (MCI)


Resarch has shown that the female hormone oestrogen plays an important part in cognition in women.  The role of testosterone in men for cognitive function is more uncertain.

Animal studies suggest mechanisms for sex hormones including testosterone to maintain optimal cognitive function. But, there are studies to suggest that endogenous testosterone levels are associated with aggression in men with cognitive impairment.

There is less research into how testosterone levels affect cognition in men. A review of studies in 2008 showed that some men having prostate cancer treatment to lower testosterone levels had cognitive impairment. Between about half (47%) and about two thirds (69%) of the men in these studies had these types of changes. The men showed difficulty in coping with problems that involved mentally rotating objects in space (spatial ability) and problems with multi tasking.

A pilot study on men in 2004 showed no significant changes in behavior, function, depression, or cognitive performance occurred following 12 weeks of testosterone replacement in men with low testosterone levels and early-to-moderate cognitive impairment.

Bottom line:  It is uncertain if low testosterone levels in men affect their cognitive function.


Enhanced by Zemanta

2 Comments to Does low testosterone in men lead to difficulties with concentration and memory ?

  1. sarky

    Seriously 12 weeks of TRT is not very likely to show very much of anything even in someone with an alleged moderate-low level as 12 weeks barely covers the initial introductory period and frequently the dose needs to be adjusted at 12 weekly intervals.

  2. sarky

    A drop in testosterone levels is generally associated with fatigue and night sweating. Impaired sleep quality which cannot be adequately rectified by either sleeping tablets or antidepressants and is as a consequence of both fatigue and night sweating will lead to memory impairment and elements of confusion. Feel free to dispute this but first consider how the general population reacts to situations involving loss of sleep and an inability to decide upon what to do in thought provoking circumstances simply because of sleep deprivation. In such cases their difficulties will be remedied by a good nights sleep now consider someone who cannot get a good nights sleep due to persisting fatigue and is still expected to perform their daily routines. Do you really imagine that there are no consequences?

Leave a Reply to sarky Cancel reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>

Doctor Björnsson
Dr. Gudmundur Björnsson is an icelandic physician, a specialist in medical rehabilitation, a certified independent medical examineer (CIME) and an MBA. He now runs his own company as a medical advisor mostly in insurance medicine. He has previously been a head of a rehabilitation clinic and president IMA. read more

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Follow me on Twitter

  • No tweets were found.


Get every new post delivered to your Inbox

Join other followers: